At one time or another everyone annoys someone else, but among the things that piss me off:
- Distracted drivers (people who talk on cell phones, eat, or do their makeup while driving).
- Bike messengers who ride on the wrong side of the street.
- People who ask directions at a bus stop or subway station when a map is right in front of them.
- Rude people, especially anyone who's rude to (or who tries to humiliate) a restaurant server.
- Racists (including racism in the porn business).
- Greed (especially corporate greed).
- Computer bullies, the people who post vile stuff online they'd never say to someone in person (I see it here all the time).