I use Firefox almost exclusively. On some rare occasions only IE will work - like when you need to get something from M-Soft.
Firefox is hands down better than Chrome (today).
No doubt FF and have not been infected with a Trojan/spyware since using it.
I use an addon called NoScript for Firefox. It automatically blocks scripts from every site until you allow them. It's a pain in the beginning because it prevents java scripts, flash players, certain images etc. on all sites - but eventually when you've allowed your favorite addresses it's nice.Same here. FF with AdBlock Plus.